Pop star Britney Spears has become only the second artist in the US chart's 52-year history to have more than one single top the chart in its opening week, according to Billboard.
Hold It Against Me is the fourth number one single of Spears' career.
In 2009, the singer's track 3 also debuted at number one.
Mariah Carey is the only other artist to have had multiple first-week chart toppers - Fantasy and One Sweet Day in 1995 and Honey in 1997.
Hold It Against Me sold 411,000 downloads, according to Nielsen SoundScan.
It marks the highest first-week tally for a solo female artist, beating the 325,000 downloads sold by Taylor Swift's Today Was a Fairytale in February 2010.
Bruno Mars features twice in this week's top ten at number two and in tenth place with Grenade and Just The Way You Are.
Katy Perry's Firework track was in third place, followed by Rihanna's What's My Name?, with Wiz Khalifa at number five.
Enrique Iglesias, Kesha, Pink and The Black Eyed Peas rounded off the top 10.
Source BBC NEWS