Madonna will take center stage at halftime of Super Bowl XLVI, flanked by Cirque du Soleil performers in what traditionally is one of the year's most watched shows.
The NFL announced Sunday night, in a press release, that the Michigan-born singer would headline the halftime show on February 5, 2012, at Lucas Oil Stadium in Indianapolis.
She follows other high-profile acts in recent years, including the Black Eyed Peas and Usher during the most recent edition of pro football's championship game at Cowboys Stadium in Texas.
Other past performers including Bruce Springsteen, Prince, The Rolling Stones and Paul McCartney. The halftime show has also been the subject of controversy, specifically in 2004 during Janet Jackson's infamous "wardrobe malfunction" while singing alongside Justin Timberlake.
The league calls the show "the most-watched musical event of the year," with more than 162 million people tuning in last year in the United States alone.
A 2008 Rock and Roll Hall of Fame inductee, Madonna is ranked by the Guinness Book of World Records as the top-selling female recording artist of all time.
She erupted on the scene in the '80s, selling 60 million records that decade and scoring several No. 1 hits including "Like a Virgin," "Papa Don't Preach" and "Crazy for You."
She continued her momentum in the 1990s with her Blonde Ambition Tour and also made headlines as a provocateur for her album "Erotica" and X-rated picture book "Sex."
Even with a growing family, Madonna has continued working -- including releasing several more albums and books. She has also acted in several films over the course of her career such as "Evita," "Desperately Seeking Susan" and "Dick Tracy."